A randomized, placebo- and active-controlled, multi-country, multi-center parallel group trial to evaluate the efficacy and safety of a fixed-dose combination of 400 mg ibuprofen and 100 mg caffeine compared with ibuprofen 400 mg and placebo in patients with acute lower back or neck pain

BACKGROUND: Ibuprofen is a well-established analgesic for acute pain symptoms. In several acute pain models, caffeine has demonstrated an analgesic adjuvant effect. This randomized trial (NCT03003000) was designed to compare the efficacy of a fixed-dose combination of ibuprofen and caffeine with ibu...

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Detalles Bibliográficos
Autores principales: Predel, Hans-Georg, Ebel-Bitoun, Caty, Lange, Robert, Weiser, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6765100/
https://www.ncbi.nlm.nih.gov/pubmed/31576162
http://dx.doi.org/10.2147/JPR.S217045

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6765100/
https://www.ncbi.nlm.nih.gov/pubmed/31576162
http://dx.doi.org/10.2147/JPR.S217045

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