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A deep learning genome-mining strategy for biosynthetic gene cluster prediction

Natural products represent a rich reservoir of small molecule drug candidates utilized as antimicrobial drugs, anticancer therapies, and immunomodulatory agents. These molecules are microbial secondary metabolites synthesized by co-localized genes termed Biosynthetic Gene Clusters (BGCs). The increa...

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Detalles Bibliográficos
Autores principales: Hannigan, Geoffrey D, Prihoda, David, Palicka, Andrej, Soukup, Jindrich, Klempir, Ondrej, Rampula, Lena, Durcak, Jindrich, Wurst, Michael, Kotowski, Jakub, Chang, Dan, Wang, Rurun, Piizzi, Grazia, Temesi, Gergely, Hazuda, Daria J, Woelk, Christopher H, Bitton, Danny A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6765103/
https://www.ncbi.nlm.nih.gov/pubmed/31400112
http://dx.doi.org/10.1093/nar/gkz654