Circularization of flavivirus genomic RNA inhibits de novo translation initiation

Members of the Flaviviridae family, including dengue virus (DENV) and yellow fever virus, cause serious disease in humans, whilst maternal infection with Zika virus (ZIKV) can induce microcephaly in newborns. Following infection, flaviviral RNA genomes are translated to produce the viral replication...

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Detalles Bibliográficos
Autores principales: Sanford, Thomas J, Mears, Harriet V, Fajardo, Teodoro, Locker, Nicolas, Sweeney, Trevor R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
RNA and RNA-protein complexes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6765113/
https://www.ncbi.nlm.nih.gov/pubmed/31392996
http://dx.doi.org/10.1093/nar/gkz686

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6765113/
https://www.ncbi.nlm.nih.gov/pubmed/31392996
http://dx.doi.org/10.1093/nar/gkz686

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