Cargando…

DNA skybridge: 3D structure producing a light sheet for high-throughput single-molecule imaging

Real-time visualization of single-proteins or -complexes on nucleic acid substrates is an essential tool for characterizing nucleic acid binding proteins. Here, we present a novel surface-condition independent and high-throughput single-molecule optical imaging platform called ‘DNA skybridge’. The D...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Daehyung, Rashid, Fahad, Cho, Yeonmo, Zaher, Manal S, Cho, I I Hwan, Hamdan, Samir M, Jeong, Cherlhyun, Lee, Jong-Bong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6765118/
https://www.ncbi.nlm.nih.gov/pubmed/31340015
http://dx.doi.org/10.1093/nar/gkz625