Polymerase synthesis of four-base DNA from two stable dimeric nucleotides

We document the preparation and properties of dimerized pentaphosphate-bridged deoxynucleotides (dicaptides) that contain reactive components of two different nucleotides simultaneously. Importantly, dicaptides are found to be considerably more stable to hydrolysis than standard dNTPs. Steady-state...

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Detalles Bibliográficos
Autores principales: Mohsen, Michael G, Ji, Debin, Kool, Eric T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Chemical Biology and Nucleic Acid Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6765132/
https://www.ncbi.nlm.nih.gov/pubmed/31504784
http://dx.doi.org/10.1093/nar/gkz741

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6765132/
https://www.ncbi.nlm.nih.gov/pubmed/31504784
http://dx.doi.org/10.1093/nar/gkz741

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