Structure and DNA damage-dependent derepression mechanism for the XRE family member DG-DdrO

DdrO is an XRE family transcription repressor that, in coordination with the metalloprotease PprI, is critical in the DNA damage response of Deinococcus species. Here, we report the crystal structure of Deinococcus geothermalis DdrO. Biochemical and structural studies revealed the conserved recogniz...

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Detalles Bibliográficos
Autores principales: Lu, Huizhi, Wang, Liangyan, Li, Shengjie, Pan, Chaoming, Cheng, Kaiying, Luo, Yuxia, Xu, Hong, Tian, Bing, Zhao, Ye, Hua, Yuejin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6765133/
https://www.ncbi.nlm.nih.gov/pubmed/31410466
http://dx.doi.org/10.1093/nar/gkz720

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6765133/
https://www.ncbi.nlm.nih.gov/pubmed/31410466
http://dx.doi.org/10.1093/nar/gkz720

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