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Molecular characteristics of reiterative DNA unwinding by the Caenorhabditis elegans RecQ helicase

The RecQ family of helicases is highly conserved both structurally and functionally from bacteria to humans. Defects in human RecQ helicases are associated with genetic diseases that are characterized by cancer predisposition and/or premature aging. RecQ proteins exhibit 3′-5′ helicase activity and...

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Detalles Bibliográficos
Autores principales: Choi, Seoyun, Lee, Seung-Won, Kim, Hajin, Ahn, Byungchan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6765134/
https://www.ncbi.nlm.nih.gov/pubmed/31435650
http://dx.doi.org/10.1093/nar/gkz708