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Molecular characteristics of reiterative DNA unwinding by the Caenorhabditis elegans RecQ helicase
The RecQ family of helicases is highly conserved both structurally and functionally from bacteria to humans. Defects in human RecQ helicases are associated with genetic diseases that are characterized by cancer predisposition and/or premature aging. RecQ proteins exhibit 3′-5′ helicase activity and...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6765134/ https://www.ncbi.nlm.nih.gov/pubmed/31435650 http://dx.doi.org/10.1093/nar/gkz708 |