Insights into the base-pairing preferences of 8-oxoguanosine on the ribosome

Of the four bases, guanine is the most susceptible to oxidation, which results in the formation of 8-oxoguanine (8-oxoG). In protein-free DNA, 8-oxodG adopts the syn conformation more frequently than the anti one. In the syn conformation, 8-oxodG base pairs with dA. The equilibrium between the anti...

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Detalles Bibliográficos
Autores principales: Thomas, Erica N, Simms, Carrie L, Keedy, Hannah E, Zaher, Hani S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
RNA and RNA-protein complexes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6765139/
https://www.ncbi.nlm.nih.gov/pubmed/31400119
http://dx.doi.org/10.1093/nar/gkz701

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6765139/
https://www.ncbi.nlm.nih.gov/pubmed/31400119
http://dx.doi.org/10.1093/nar/gkz701

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