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DNA-PK(cs) promotes chromatin decondensation to facilitate initiation of the DNA damage response
The DNA damage response (DDR) encompasses the cellular response to DNA double-stranded breaks (DSBs), and includes recognition of the DSB, recruitment of numerous factors to the DNA damage site, initiation of signaling cascades, chromatin remodeling, cell-cycle checkpoint activation, and repair of t...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6765147/ https://www.ncbi.nlm.nih.gov/pubmed/31396623 http://dx.doi.org/10.1093/nar/gkz694 |