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DNA-PK(cs) promotes chromatin decondensation to facilitate initiation of the DNA damage response

The DNA damage response (DDR) encompasses the cellular response to DNA double-stranded breaks (DSBs), and includes recognition of the DSB, recruitment of numerous factors to the DNA damage site, initiation of signaling cascades, chromatin remodeling, cell-cycle checkpoint activation, and repair of t...

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Detalles Bibliográficos
Autores principales: Lu, Huiming, Saha, Janapriya, Beckmann, Pauline J, Hendrickson, Eric A, Davis, Anthony J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6765147/
https://www.ncbi.nlm.nih.gov/pubmed/31396623
http://dx.doi.org/10.1093/nar/gkz694