USP11 acts as a histone deubiquitinase functioning in chromatin reorganization during DNA repair

How chromatin dynamics is regulated to ensure efficient DNA repair remains to be understood. Here, we report that the ubiquitin-specific protease USP11 acts as a histone deubiquitinase to catalyze H2AK119 and H2BK120 deubiquitination. We showed that USP11 is physically associated with the chromatin...

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Detalles Bibliográficos
Autores principales: Ting, Xia, Xia, Lu, Yang, Jianguo, He, Lin, Si, Wenzhe, Shang, Yongfeng, Sun, Luyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6765148/
https://www.ncbi.nlm.nih.gov/pubmed/31504778
http://dx.doi.org/10.1093/nar/gkz726

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6765148/
https://www.ncbi.nlm.nih.gov/pubmed/31504778
http://dx.doi.org/10.1093/nar/gkz726

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