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USP11 acts as a histone deubiquitinase functioning in chromatin reorganization during DNA repair
How chromatin dynamics is regulated to ensure efficient DNA repair remains to be understood. Here, we report that the ubiquitin-specific protease USP11 acts as a histone deubiquitinase to catalyze H2AK119 and H2BK120 deubiquitination. We showed that USP11 is physically associated with the chromatin...
Autores principales: | Ting, Xia, Xia, Lu, Yang, Jianguo, He, Lin, Si, Wenzhe, Shang, Yongfeng, Sun, Luyang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6765148/ https://www.ncbi.nlm.nih.gov/pubmed/31504778 http://dx.doi.org/10.1093/nar/gkz726 |
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