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KRAS, NRAS, BRAF, HER2 and Microsatellite Instability in Metastatic Colorectal Cancer – Practical Implications for the Clinician

BACKGROUND: Colorectal cancer is a successful model of genetic biomarker development in oncology. Currently, several predictive or prognostic genetic alterations have been identified and are used in clinical practice. The RAS gene family, which includes KRAS and NRAS act as predictors for anti-epith...

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Detalles Bibliográficos
Autores principales: Afrăsânie, Vlad-Adrian, Marinca, Mihai Vasile, Alexa-Stratulat, Teodora, Gafton, Bogdan, Păduraru, Marius, Adavidoaiei, Anca Maria, Miron, Lucian, Rusu, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sciendo 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6765160/
https://www.ncbi.nlm.nih.gov/pubmed/31553708
http://dx.doi.org/10.2478/raon-2019-0033