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Kinesin-8 and Dis1/TOG collaborate to limit spindle elongation from prophase to anaphase A for proper chromosome segregation in fission yeast

High-fidelity chromosome segregation relies on proper microtubule regulation. Kinesin-8 has been shown to destabilise microtubules to reduce metaphase spindle length and chromosome movements in multiple species. XMAP215/chTOG polymerases catalyse microtubule growth for spindle assembly, elongation a...

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Detalles Bibliográficos
Autores principales: Pinder, Corinne, Matsuo, Yuzy, Maurer, Sebastian P., Toda, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6765184/
https://www.ncbi.nlm.nih.gov/pubmed/31427431
http://dx.doi.org/10.1242/jcs.232306