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Phosphorylation of importin-α1 by CDK1–cyclin B1 controls mitotic spindle assembly
Importin-α serves as an adaptor linking importin-β to proteins carrying a nuclear localization sequence (NLS). During interphase, this interaction enables nuclear protein import, while in mitosis it regulates spindle assembly factors (SAFs) and controls microtubule nucleation, stabilization and spin...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6765185/ https://www.ncbi.nlm.nih.gov/pubmed/31434716 http://dx.doi.org/10.1242/jcs.232314 |