Cargando…

A protein architecture guided screen for modification dependent restriction endonucleases

Modification dependent restriction endonucleases (MDREs) often have separate catalytic and modification dependent domains. We systematically looked for previously uncharacterized fusion proteins featuring a PUA or DUF3427 domain and HNH or PD-(D/E)XK catalytic domain. The enzymes were clustered by s...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lutz, Thomas, Flodman, Kiersten, Copelas, Alyssa, Czapinska, Honorata, Mabuchi, Megumu, Fomenkov, Alexey, He, Xinyi, Bochtler, Matthias, Xu, Shuang-yong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2019
Materias:	Nucleic Acid Enzymes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6765204/ https://www.ncbi.nlm.nih.gov/pubmed/31504772 http://dx.doi.org/10.1093/nar/gkz755

Ejemplares similares

Structure and cleavage activity of the tetrameric MspJI DNA modification-dependent restriction endonuclease
por: Horton, John R., et al.
Publicado: (2012)

Modification-dependent restriction endonuclease, MspJI, flips 5-methylcytosine out of the DNA helix
por: Horton, John R., et al.
Publicado: (2014)

Crystal structure of the modification-dependent SRA-HNH endonuclease TagI
por: Kisiala, Marlena, et al.
Publicado: (2018)

A unique family of Mrr-like modification-dependent restriction endonucleases
por: Zheng, Yu, et al.
Publicado: (2010)

Structure-guided sequence specificity engineering of the modification-dependent restriction endonuclease LpnPI
por: Sasnauskas, Giedrius, et al.
Publicado: (2015)

Catalytic domain of restriction endonuclease BmrI as a cleavage module for engineering endonucleases with novel substrate specificities
por: Chan, Siu-hong, et al.
Publicado: (2007)

Restriction glycosylases: involvement of endonuclease activities in the restriction process
por: Zhang, Yingbiao, et al.
Publicado: (2017)

Increasing cleavage specificity and activity of restriction endonuclease KpnI
por: Vasu, Kommireddy, et al.
Publicado: (2013)

Structure of HhaI endonuclease with cognate DNA at an atomic resolution of 1.0 Å
por: Horton, John R, et al.
Publicado: (2020)

Creating highly specific nucleases by fusion of active restriction endonucleases and catalytically inactive homing endonucleases
por: Fonfara, Ines, et al.
Publicado: (2012)

Type I restriction endonucleases are true catalytic enzymes
por: Bianco, Piero R., et al.
Publicado: (2009)

Characterization of the 5-hydroxymethylcytosine-specific DNA restriction endonucleases
por: Borgaro, Janine G., et al.
Publicado: (2013)

Dissociation from DNA of Type III Restriction–Modification enzymes during helicase-dependent motion and following endonuclease activity
por: Tóth, Júlia, et al.
Publicado: (2012)

Dynamics and consequences of DNA looping by the FokI restriction endonuclease
por: Catto, Lucy E., et al.
Publicado: (2008)

Natural zinc ribbon HNH endonucleases and engineered zinc finger nicking endonuclease
por: Xu, Shuang-yong, et al.
Publicado: (2013)

Concerted action at eight phosphodiester bonds by the BcgI restriction endonuclease
por: Marshall, Jacqueline J. T., et al.
Publicado: (2011)

Rational engineering of sequence specificity in R.MwoI restriction endonuclease
por: Skowronek, Krzysztof, et al.
Publicado: (2012)

The Type II restriction endonuclease MvaI has dual specificity
por: Stier, Ildikó, et al.
Publicado: (2010)

Cleavage of adenine-modified functionalized DNA by type II restriction endonucleases
por: Macíčková-Cahová, Hana, et al.
Publicado: (2009)

Structures, activity and mechanism of the Type IIS restriction endonuclease PaqCI
por: Kennedy, Madison A, et al.
Publicado: (2023)

The Helicobacter pylori HpyAXII restriction–modification system limits exogenous DNA uptake by targeting GTAC sites but shows asymmetric conservation of the DNA methyltransferase and restriction endonuclease components
por: Humbert, Olivier, et al.
Publicado: (2008)

Creation of a type IIS restriction endonuclease with a long recognition sequence
por: Lippow, Shaun M., et al.
Publicado: (2009)

Targeting individual subunits of the FokI restriction endonuclease to specific DNA strands
por: Sanders, Kelly L., et al.
Publicado: (2009)

Structural mechanisms of the degenerate sequence recognition by Bse634I restriction endonuclease
por: Manakova, Elena, et al.
Publicado: (2012)

Rational engineering of type II restriction endonuclease DNA binding and cleavage specificity
por: Morgan, Richard D., et al.
Publicado: (2009)

Cellular localization and dynamics of the Mrr type IV restriction endonuclease of Escherichia coli
por: Ghosh, Anirban, et al.
Publicado: (2014)

Restriction endonuclease triggered bacterial apoptosis as a mechanism for long time survival
por: Nagamalleswari, Easa, et al.
Publicado: (2017)

The dynamics of the monomeric restriction endonuclease BcnI during its interaction with DNA
por: Kostiuk, Georgij, et al.
Publicado: (2017)

The third restriction–modification system from Thermus aquaticus YT-1: solving the riddle of two TaqII specificities
por: Skowron, Piotr M., et al.
Publicado: (2017)

Illuminating the reaction pathway of the FokI restriction endonuclease by fluorescence resonance energy transfer
por: Pernstich, Christian, et al.
Publicado: (2012)

BspRI restriction endonuclease: cloning, expression in Escherichia coli and sequential cleavage mechanism
por: Raskó, Tamás, et al.
Publicado: (2010)

High pressure activation of the Mrr restriction endonuclease in Escherichia coli involves tetramer dissociation
por: Bourges, Anaïs C., et al.
Publicado: (2017)

DNA rehybridization drives product release from Cas9 ribonucleoprotein to enable multiple-turnover cleavage
por: Pan, Juan, et al.
Publicado: (2023)

Restriction endonuclease TseI cleaves A:A and T:T mismatches in CAG and CTG repeats
por: Ma, Long, et al.
Publicado: (2013)

Biochemical analysis of the substrate specificity and sequence preference of endonuclease IV from bacteriophage T4, a dC-specific endonuclease implicated in restriction of dC-substituted T4 DNA synthesis
por: Hirano, Nobutaka, et al.
Publicado: (2006)

A RecB-family nuclease motif in the Type I restriction endonuclease EcoR124I
por: Šišáková, Eva, et al.
Publicado: (2008)

Restriction endonuclease BpuJI specific for the 5′-CCCGT sequence is related to the archaeal Holliday junction resolvase family
por: Sukackaite, Rasa, et al.
Publicado: (2007)

S-Adenosyl homocysteine and DNA ends stimulate promiscuous nuclease activities in the Type III restriction endonuclease EcoPI
por: Peakman, Luke J., et al.
Publicado: (2009)

CgII cleaves DNA using a mechanism distinct from other ATP-dependent restriction endonucleases
por: Toliusis, Paulius, et al.
Publicado: (2017)

Nucleotide flipping by restriction enzymes analyzed by 2-aminopurine steady-state fluorescence
por: Tamulaitis, Gintautas, et al.
Publicado: (2007)

Cannot write session to /tmp/vufind_sessions/sess_6mgbkr8ov76nahtlbog9f87ka5