Glycine cleavage system determines the fate of pluripotent stem cells via the regulation of senescence and epigenetic modifications

Metabolic remodelling has emerged as critical for stem cell pluripotency; however, the underlying mechanisms have yet to be fully elucidated. Here, we found that the glycine cleavage system (GCS) is highly activated to promote stem cell pluripotency and during somatic cell reprogramming. Mechanistic...

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Detalles Bibliográficos
Autores principales: Tian, Shengya, Feng, Junru, Cao, Yang, Shen, Shengqi, Cai, Yongping, Yang, Dongdong, Yan, Ronghui, Wang, Lihua, Zhang, Huafeng, Zhong, Xiuying, Gao, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6765226/
https://www.ncbi.nlm.nih.gov/pubmed/31562192
http://dx.doi.org/10.26508/lsa.201900413

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6765226/
https://www.ncbi.nlm.nih.gov/pubmed/31562192
http://dx.doi.org/10.26508/lsa.201900413

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