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RNA editing alterations define manifestation of prion diseases

Prion diseases are fatal neurodegenerative disorders caused by misfolding of the normal prion protein into an infectious cellular pathogen. Clinically characterized by rapidly progressive dementia and accounting for 85% of human prion disease cases, sporadic Creutzfeldt–Jakob disease (sCJD) is the p...

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Detalles Bibliográficos
Autores principales: Kanata, Eirini, Llorens, Franc, Dafou, Dimitra, Dimitriadis, Athanasios, Thüne, Katrin, Xanthopoulos, Konstantinos, Bekas, Nikolaos, Espinosa, Juan Carlos, Schmitz, Matthias, Marín-Moreno, Alba, Capece, Vincenzo, Shormoni, Orr, Andréoletti, Olivier, Bonn, Stefan, Torres, Juan María, Ferrer, Isidre, Zerr, Inga, Sklaviadis, Theodoros
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6765247/
https://www.ncbi.nlm.nih.gov/pubmed/31492812
http://dx.doi.org/10.1073/pnas.1803521116