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Spatial transcriptome profiling by MERFISH reveals subcellular RNA compartmentalization and cell cycle-dependent gene expression

The expression profiles and spatial distributions of RNAs regulate many cellular functions. Image-based transcriptomic approaches provide powerful means to measure both expression and spatial information of RNAs in individual cells within their native environment. Among these approaches, multiplexed...

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Detalles Bibliográficos
Autores principales: Xia, Chenglong, Fan, Jean, Emanuel, George, Hao, Junjie, Zhuang, Xiaowei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6765259/
https://www.ncbi.nlm.nih.gov/pubmed/31501331
http://dx.doi.org/10.1073/pnas.1912459116