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A New Regulatory Mechanism Between P53 And YAP Crosstalk By SIRT1 Mediated Deacetylation To Regulate Cell Cycle And Apoptosis In A549 Cell Lines

BACKGROUND: Yes-associated protein (YAP) is downstream of the Hippo signaling pathway, which regulates several cellular processes. P53 is a key transcriptional regulator that responds to a variety of cellular stresses and regulates key cellular processes such as DNA repair, cell-cycle progression, a...

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Detalles Bibliográficos
Autores principales: Yuan, Fang, Wang, Jinliang, Li, Ruixin, Zhao, Xiao, Zhang, Yuxuan, Liu, Biao, Lei, Yonghong, Hu, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6765265/
https://www.ncbi.nlm.nih.gov/pubmed/31576168
http://dx.doi.org/10.2147/CMAR.S214826