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Effects of the selective GPER1 agonist G1 on bone growth

Estrogens may affect bone growth locally or systemically via the known estrogen receptors ESR1, ESR2 and G protein-coupled estrogen receptor 1 (GPER1). Mouse and human growth plate chondrocytes have been demonstrated to express GPER1 and ablation of this receptor increased bone length in mice. There...

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Detalles Bibliográficos
Autores principales: Iravani, Maryam, Lagerquist, Marie K, Karimian, Elham, Chagin, Andrei S, Ohlsson, Claes, Sävendahl, Lars
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6765336/
https://www.ncbi.nlm.nih.gov/pubmed/31434056
http://dx.doi.org/10.1530/EC-19-0274