Cargando…

Effects of the selective GPER1 agonist G1 on bone growth

Estrogens may affect bone growth locally or systemically via the known estrogen receptors ESR1, ESR2 and G protein-coupled estrogen receptor 1 (GPER1). Mouse and human growth plate chondrocytes have been demonstrated to express GPER1 and ablation of this receptor increased bone length in mice. There...

Descripción completa

Detalles Bibliográficos
Autores principales:	Iravani, Maryam, Lagerquist, Marie K, Karimian, Elham, Chagin, Andrei S, Ohlsson, Claes, Sävendahl, Lars
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Bioscientifica Ltd 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6765336/ https://www.ncbi.nlm.nih.gov/pubmed/31434056 http://dx.doi.org/10.1530/EC-19-0274

Ejemplares similares

Resveratrol Treatment Delays Growth Plate Fusion and Improves Bone Growth in Female Rabbits
por: Karimian, Elham, et al.
Publicado: (2013)

Genetic Regulation of the Growth Plate
por: Karimian, Elham, et al.
Publicado: (2012)

Molecular Characterization of the Dual Effect of the GPER Agonist G-1 in Glioblastoma
por: Hirtz, Alex, et al.
Publicado: (2022)

GPER agonist G-1 decreases adrenocortical carcinoma (ACC) cell growth in vitro and in vivo
por: Chimento, Adele, et al.
Publicado: (2015)

Activation of mTORC1 in chondrocytes does not affect proliferation or differentiation, but causes the resting zone of the growth plate to become disordered
por: Newton, Phillip T., et al.
Publicado: (2018)

GPER Agonist G-1 Disrupts Tubulin Dynamics and Potentiates Temozolomide to Impair Glioblastoma Cell Proliferation
por: Hirtz, Alex, et al.
Publicado: (2021)

Pharmacological inhibition of BCL-2 with the FDA-approved drug venetoclax impairs longitudinal bone growth
por: Velentza, Lilly, et al.
Publicado: (2023)

Correlation of functional and radioligand binding characteristics of GPER ligands confirming aldosterone as a GPER agonist
por: Ding, Qingming, et al.
Publicado: (2022)

GPER Agonist G1 Prevents Wnt-Induced JUN Upregulation in HT29 Colorectal Cancer Cells
por: Abancens, Maria, et al.
Publicado: (2022)

Periarticular Bone Loss in Antigen-Induced Arthritis
por: Engdahl, Cecilia, et al.
Publicado: (2013)

Transcriptomic data of MCF-7 breast cancer cells treated with G1, a G-protein coupled estrogen receptor (GPER) agonist()
por: Pal, Uttariya, et al.
Publicado: (2022)

GPER agonist G1 suppresses neuronal apoptosis mediated by endoplasmic reticulum stress after cerebral ischemia/reperfusion injury
por: Han, Zi-Wei, et al.
Publicado: (2019)

G-Protein-Coupled Estrogen Receptor (GPER)-Specific Agonist G1 Induces ER Stress Leading to Cell Death in MCF-7 Cells
por: Vo, Diep-Khanh Ho, et al.
Publicado: (2019)

Attenuation of Salt-Induced Cardiac Remodeling and Diastolic Dysfunction by the GPER Agonist G-1 in Female mRen2.Lewis Rats
por: Jessup, Jewell A., et al.
Publicado: (2010)

Effects of ICI 182,780, an ERα and ERβ antagonist, and G-1, a GPER agonist, on autophagy in breast cancer cells
por: Muler, Mari Luminosa, et al.
Publicado: (2020)

GPER-independent inhibition of adrenocortical cancer growth by G-1 involves ROS/Egr-1/BAX pathway
por: Casaburi, Ivan, et al.
Publicado: (2017)

The gut microbiota regulates bone mass in mice
por: Sjögren, Klara, et al.
Publicado: (2012)

Reduced Bone Mass and Muscle Strength in Male 5α-Reductase Type 1 Inactivated Mice
por: Windahl, Sara H., et al.
Publicado: (2011)

The GPER Agonist LNS8801 Induces Mitotic Arrest and Apoptosis in Uveal Melanoma Cells
por: Ambrosini, Grazia, et al.
Publicado: (2023)

Secular Trends in Pubertal Growth Acceleration in Swedish Boys Born From 1947 to 1996
por: Ohlsson, Claes, et al.
Publicado: (2019)

NHERF1, a novel GPER associated protein, increases stability and activation of GPER in ER-positive breast cancer
por: Meng, Ran, et al.
Publicado: (2016)

Activation of G-Protein-Coupled Estrogen Receptor 1 (GPER1) Reduces Progression of Vulvar Carcinoma Cells
por: Loris, Johanna, et al.
Publicado: (2023)

Decreased Expression of GPER1 Gene and Protein in Goiter
por: Weber, Raquel, et al.
Publicado: (2015)

Serum levels of GPER-1 in euthymic bipolar patients
por: Orhan, Fatma Özlem, et al.
Publicado: (2018)

A Cell-Based Method to Detect Agonist and Antagonist Activities of Endocrine-Disrupting Chemicals on GPER
por: Périan, Séverine, et al.
Publicado: (2020)

Promising Perspectives of the Antiproliferative GPER Inverse Agonist ERα17p in Breast Cancer
por: Kampa, Marilena, et al.
Publicado: (2023)

Trabecular bone loss in collagen antibody-induced arthritis
por: Grahnemo, Louise, et al.
Publicado: (2015)

Targeting the G protein-coupled estrogen receptor (GPER) in obesity and diabetes
por: Sharma, Geetanjali, et al.
Publicado: (2021)

The G protein-coupled oestrogen receptor GPER in health and disease: an update
por: Prossnitz, Eric R., et al.
Publicado: (2023)

Low expression of G protein-coupled oestrogen receptor 1 (GPER) is associated with adverse survival of breast cancer patients
por: Martin, Stewart G., et al.
Publicado: (2018)

Proteomic Analyses of the G Protein-Coupled Estrogen Receptor GPER1 Reveal Constitutive Links to Endoplasmic Reticulum, Glycosylation, Trafficking, and Calcium Signaling
por: Ahmadian Elmi, Maryam, et al.
Publicado: (2023)

Association between GPER gene polymorphisms and GPER expression levels with cancer predisposition and progression
por: Ulhaq, Zulvikar Syambani, et al.
Publicado: (2021)

Role of endogenous and exogenous female sex hormones in arthritis and osteoporosis development in B10.Q-ncf1(*/* )mice with collagen-induced chronic arthritis
por: Jochems, Caroline, et al.
Publicado: (2010)

GPER-1 acts as a tumor suppressor in ovarian cancer
por: Ignatov, Tanja, et al.
Publicado: (2013)

Does GPER1 Play a Role in Sexual Dimorphism?
por: Dovey, Janine L., et al.
Publicado: (2020)

Editorial: GPER and Human Pathologies
por: Jacquot, Yves, et al.
Publicado: (2021)

Editorial: GPER: Control and Functions
por: Jacquot, Yves, et al.
Publicado: (2021)

G protein-coupled estrogen receptor 1 (GPER) activation triggers different signaling pathways on neurons and astrocytes
por: Roque, Cláudio, et al.
Publicado: (2019)

G Protein-Coupled Estrogen Receptor, GPER1, Offers a Novel Target for the Treatment of Digestive Diseases
por: DeLeon, Chelsea, et al.
Publicado: (2020)

G-protein Coupled Estrogen Receptor (GPER/GPR30) and Women's Health
por: Kim, Mi-Jin, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_i38usvosqo5l0isa7grh47ole7