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Inhibition of microRNA-141-3p Reduces Hypoxia-Induced Apoptosis in H9c2 Rat Cardiomyocytes by Activating the RP105-Dependent PI3K/AKT Signaling Pathway

BACKGROUND: Oxidative stress in myocardial ischemia results in cardiomyocyte apoptosis. The expression of microRNA-141-3p (miR-141-3p) and the 105 kD toll-like receptor protein (TLR), RP105, have been identified in cardiomyocytes in vitro. This study aimed to investigate the effects of hypoxia in H9...

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Detalles Bibliográficos
Autores principales: Qin, Qiaoji, Cui, Liqiang, Zhou, Zhenggang, Zhang, Zhirong, Wang, Yini, Zhou, Changyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6765341/
https://www.ncbi.nlm.nih.gov/pubmed/31532760
http://dx.doi.org/10.12659/MSM.916361