Physiologically‐Based Pharmacokinetic Modeling Approach to Predict Rifampin‐Mediated Intestinal P‐Glycoprotein Induction

Physiologically‐based pharmacokinetic (PBPK) modeling is a powerful tool to quantitatively describe drug disposition profiles in vivo, thereby providing an alternative to predict drug–drug interactions (DDIs) that have not been tested clinically. This study aimed to predict effects of rifampin‐media...

Descripción completa

Detalles Bibliográficos
Autores principales: Yamazaki, Shinji, Costales, Chester, Lazzaro, Sarah, Eatemadpour, Soraya, Kimoto, Emi, Varma, Manthena V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6765699/
https://www.ncbi.nlm.nih.gov/pubmed/31420942
http://dx.doi.org/10.1002/psp4.12458

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6765699/
https://www.ncbi.nlm.nih.gov/pubmed/31420942
http://dx.doi.org/10.1002/psp4.12458

Ejemplares similares