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Peroxiredoxin III Protects Tumor Suppressor PTEN from Oxidation by 15-Hydroperoxy-eicosatetraenoic Acid

Phosphatase and tensin homolog deleted on chromosome 10 (PTEN) is a lipid and protein phosphatase that coordinates various cellular processes. Its activity is regulated by the reversible oxidation of an active-site cysteine residue by H(2)O(2) and thioredoxin. However, the potential role of lipid pe...

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Detalles Bibliográficos
Autores principales: Zhang, Ying, Park, Jiyoung, Han, Seong-Jeong, Lim, Yongwoon, Park, Iha, Kim, Jong-Suk, Woo, Hyun Ae, Lee, Seung-Rock
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6766106/
https://www.ncbi.nlm.nih.gov/pubmed/31636803
http://dx.doi.org/10.1155/2019/2828493