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Stimulation of Na(+)/K(+)-ATPase with an Antibody against Its 4(th) Extracellular Region Attenuates Angiotensin II-Induced H9c2 Cardiomyocyte Hypertrophy via an AMPK/SIRT3/PPARγ Signaling Pathway

Activation of the renin-angiotensin system (RAS) contributes to the pathogenesis of cardiovascular diseases. Sodium potassium ATPase (NKA) expression and activity are often regulated by angiotensin II (Ang II). This study is aimed at investigating whether DR-Ab, an antibody against 4(th) extracellul...

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Detalles Bibliográficos
Autores principales: Xiong, Siping, Sun, Hai-Jian, Cao, Lei, Zhu, Mengyuan, Liu, Tengteng, Wu, Zhiyuan, Bian, Jin-Song
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6766118/
https://www.ncbi.nlm.nih.gov/pubmed/31636805
http://dx.doi.org/10.1155/2019/4616034