Cargando…
Stimulation of Na(+)/K(+)-ATPase with an Antibody against Its 4(th) Extracellular Region Attenuates Angiotensin II-Induced H9c2 Cardiomyocyte Hypertrophy via an AMPK/SIRT3/PPARγ Signaling Pathway
Activation of the renin-angiotensin system (RAS) contributes to the pathogenesis of cardiovascular diseases. Sodium potassium ATPase (NKA) expression and activity are often regulated by angiotensin II (Ang II). This study is aimed at investigating whether DR-Ab, an antibody against 4(th) extracellul...
Autores principales: | Xiong, Siping, Sun, Hai-Jian, Cao, Lei, Zhu, Mengyuan, Liu, Tengteng, Wu, Zhiyuan, Bian, Jin-Song |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6766118/ https://www.ncbi.nlm.nih.gov/pubmed/31636805 http://dx.doi.org/10.1155/2019/4616034 |
Ejemplares similares
-
Na(+)/K(+)-ATPase-dependent autophagy protects brain against ischemic injury
por: Zhu, Mengyuan, et al.
Publicado: (2020) -
Anti–Na(+)/K(+)-ATPase immunotherapy ameliorates α-synuclein pathology through activation of Na(+)/K(+)-ATPase α1–dependent autophagy
por: Cao, Lei, et al.
Publicado: (2021) -
Crosstalk between AMPK activation and angiotensin II-induced hypertrophy in cardiomyocytes: the role of mitochondria
por: Hernández, Jessica Soto, et al.
Publicado: (2014) -
SIRT1 Functions as an Important Regulator of Estrogen-Mediated Cardiomyocyte Protection in Angiotensin II-Induced Heart Hypertrophy
por: Shen, Tao, et al.
Publicado: (2014) -
DR-region of Na(+)/K(+) ATPase is a target to treat excitotoxicity and stroke
por: Shi, Meimei, et al.
Publicado: (2018)