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Yttrium-90-Labeled Anti-Glypican 3 Radioimmunotherapy Halts Tumor Growth in an Orthotopic Xenograft Model of Hepatocellular Carcinoma

Hepatocellular carcinoma (HCC) is the second most lethal malignancy globally and is increasing in incidence in the United States. Unfortunately, there are few effective systemic treatment options, particularly for disseminated disease. Glypican-3 (GPC3) is a proteoglycan cell surface receptor overex...

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Detalles Bibliográficos
Autores principales: Ludwig, Andrew D., Labadie, Kevin P., Seo, Y. David, Hamlin, Donald K., Nguyen, Holly M., Mahadev, Vimukta M., Yeung, Raymond S., Wilbur, D. S., Park, James O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6766125/
https://www.ncbi.nlm.nih.gov/pubmed/31636665
http://dx.doi.org/10.1155/2019/4564707