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Diverse Effects of Lysophosphatidic Acid Receptors on Ovarian Cancer Signaling Pathways
Lysophosphatidic acid (LPA) is a bioactive phospholipid with mitogenic and growth factor-like activities affecting cell invasion, cancer progression, and resistance. It is produced mainly by autotaxin and acts on six G-protein-coupled receptors, LPAR1-6. LPA has recently been implicated as a growth...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6766155/ https://www.ncbi.nlm.nih.gov/pubmed/31636669 http://dx.doi.org/10.1155/2019/7547469 |