Pharmacokinetics of mycophenolic acid and its effect on CD4(+) and CD8(+) T cells after oral administration of mycophenolate mofetil to healthy cats

BACKGROUND: Mycophenolate mofetil (MMF) is an immunosuppressant used in human and veterinary medicine. Little pharmacokinetic and pharmacodynamic information on MMF is available in cats. OBJECTIVE: To evaluate the plasma disposition of mycophenolic acid (MPA) and assess its effect on total periphera...

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Detalles Bibliográficos
Autores principales: Slovak, Jennifer E., Hwang, Julianne K., Rivera, Sol M., Villarino, Nicolas F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2019
Materias:
SMALL ANIMAL
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6766527/
https://www.ncbi.nlm.nih.gov/pubmed/31423655
http://dx.doi.org/10.1111/jvim.15585

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6766527/
https://www.ncbi.nlm.nih.gov/pubmed/31423655
http://dx.doi.org/10.1111/jvim.15585

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