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Pharmacokinetics of mycophenolic acid and its effect on CD4(+) and CD8(+) T cells after oral administration of mycophenolate mofetil to healthy cats
BACKGROUND: Mycophenolate mofetil (MMF) is an immunosuppressant used in human and veterinary medicine. Little pharmacokinetic and pharmacodynamic information on MMF is available in cats. OBJECTIVE: To evaluate the plasma disposition of mycophenolic acid (MPA) and assess its effect on total periphera...
Autores principales: | Slovak, Jennifer E., Hwang, Julianne K., Rivera, Sol M., Villarino, Nicolas F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6766527/ https://www.ncbi.nlm.nih.gov/pubmed/31423655 http://dx.doi.org/10.1111/jvim.15585 |
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