Gene Modification and Three‐Dimensional Scaffolds as Novel Tools to Allow the Use of Postnatal Thymic Epithelial Cells for Thymus Regeneration Approaches

Defective functionality of thymic epithelial cells (TECs), due to genetic mutations or injuring causes, results in altered T‐cell development, leading to immunodeficiency or autoimmunity. These defects cannot be corrected by hematopoietic stem cell transplantation (HSCT), and thymus transplantation...

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Detalles Bibliográficos
Autores principales: Bortolomai, Ileana, Sandri, Monica, Draghici, Elena, Fontana, Elena, Campodoni, Elisabetta, Marcovecchio, Genni Enza, Ferrua, Francesca, Perani, Laura, Spinelli, Antonello, Canu, Tamara, Catucci, Marco, Di Tomaso, Tiziano, Sergi Sergi, Lucia, Esposito, Antonio, Lombardo, Angelo, Naldini, Luigi, Tampieri, Anna, Hollander, Georg A., Villa, Anna, Bosticardo, Marita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2019
Materias:
Tissue Engineering and Regenerative Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6766605/
https://www.ncbi.nlm.nih.gov/pubmed/31140762
http://dx.doi.org/10.1002/sctm.18-0218

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6766605/
https://www.ncbi.nlm.nih.gov/pubmed/31140762
http://dx.doi.org/10.1002/sctm.18-0218

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