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NEAT1 is overexpressed in Parkinson’s disease substantia nigra and confers drug-inducible neuroprotection from oxidative stress

Recent reports attribute numerous regulatory functions to the nuclear paraspeckle-forming long noncoding RNA, nuclear enriched assembly transcript 1 (NEAT1), but the implications of its involvement in Parkinson’s disease (PD) remain controversial. To address this issue, we assessed NEAT1 expression...

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Detalles Bibliográficos
Autores principales: Simchovitz, Alon, Hanan, Mor, Niederhoffer, Naomi, Madrer, Nimrod, Yayon, Nadav, Bennett, Estelle R., Greenberg, David S., Kadener, Sebastian, Soreq, Hermona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Federation of American Societies for Experimental Biology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6766647/
https://www.ncbi.nlm.nih.gov/pubmed/31311324
http://dx.doi.org/10.1096/fj.201900830R