No Clinically Relevant Interactions of St. John's Wort Extract Ze 117 Low in Hyperforin With Cytochrome P450 Enzymes and P‐glycoprotein

Hypericum perforatum L. (St. John's wort) is used to treat mild‐to‐moderate depression. Its potential safety risks are pharmacokinetic drug interactions via cytochrome P450 (CYP) enzymes and P‐glycoprotein, presumably caused by hyperforin. In a phase I, open‐label, nonrandomized, single‐sequenc...

Descripción completa

Detalles Bibliográficos
Autores principales: Zahner, Catherine, Kruttschnitt, Esther, Uricher, Julia, Lissy, Michael, Hirsch, Martin, Nicolussi, Simon, Krähenbühl, Stephan, Drewe, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6766782/
https://www.ncbi.nlm.nih.gov/pubmed/30739325
http://dx.doi.org/10.1002/cpt.1392

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6766782/
https://www.ncbi.nlm.nih.gov/pubmed/30739325
http://dx.doi.org/10.1002/cpt.1392

Ejemplares similares