Pharmacokinetics, Safety, and Tolerability of Tezepelumab (AMG 157) in Healthy and Atopic Dermatitis Adult Subjects

Tezepelumab (AMG 157) is a monoclonal antibody that targets thymic stromal lymphopoietin and has shown benefits in treating asthma. We assessed the safety, tolerability, and pharmacokinetics of single‐ascending and multiple‐ascending doses in two randomized, double‐blind, placebo‐controlled phase I...

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Detalles Bibliográficos
Autores principales: Parnes, Jane R., Sullivan, John T., Chen, Li, Dias, Clapton
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6766783/
https://www.ncbi.nlm.nih.gov/pubmed/30779339
http://dx.doi.org/10.1002/cpt.1401

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6766783/
https://www.ncbi.nlm.nih.gov/pubmed/30779339
http://dx.doi.org/10.1002/cpt.1401

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