Cargando…

SB365, Pulsatilla Saponin D Induces Caspase-Independent Cell Death and Augments the Anticancer Effect of Temozolomide in Glioblastoma Multiforme Cells

SB365, a saponin D extracted from the roots of Pulsatilla koreana, has been reported to show cytotoxicity in several cancer cell lines. We investigated the effects of SB365 on U87-MG and T98G glioblastoma multiforme (GBM) cells, and its efficacy in combination with temozolomide for treating GBM. SB3...

Descripción completa

Detalles Bibliográficos
Autores principales: Hong, Jun-Man, Kim, Jin-Hee, Kim, Hyemin, Lee, Wang Jae, Hwang, Young-il
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6766801/
https://www.ncbi.nlm.nih.gov/pubmed/31491945
http://dx.doi.org/10.3390/molecules24183230