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LC–MS/MS Method for Simultaneous Determination of Linarin and Its Metabolites in Rat Plasma and Liver Tissue Samples: Application to Pharmacokinetic and Liver Tissue Distribution Study After Oral Administration of Linarin

Linarin, a flavone glycoside, is considered to be a promising natural product due to its diverse pharmacological activities. Recently, it has been brought into focus for its potential to treat liver failure. In this study, a rapid and sensitive liquid chromatography electrospray-ionization tandem ma...

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Detalles Bibliográficos
Autores principales: Li, Yang, Guang, Chenxi, Zhao, Na, Feng, Xinchi, Qiu, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6766828/
https://www.ncbi.nlm.nih.gov/pubmed/31540332
http://dx.doi.org/10.3390/molecules24183342