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Hypoxia‐responsive miRNA‐21‐5p inhibits Runx2 suppression by targeting SMAD7 in MC3T3‐E1 cells

Sustained hypoxia inhibits osteogenesis and osteoblast differentiation by downregulating the expression of runt‐related transcription factor 2 (Runx2). MicroRNAs (miRNAs) have been shown to regulate osteogenesis and osteoblast differentiation. In the present study, we profiled miRNAs, with microRNA...

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Detalles Bibliográficos
Autores principales: Li, Lujun, Jiang, Dianming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6766843/
https://www.ncbi.nlm.nih.gov/pubmed/31106445
http://dx.doi.org/10.1002/jcb.28944