A Dogma in Doubt: Hydrolysis of Equatorial Ligands of Pt(IV) Complexes under Physiological Conditions

Due to their high kinetic inertness and consequently reduced side reactions with biomolecules, Pt(IV) complexes are considered to define the future of anticancer platinum drugs. The aqueous stability of a series of biscarboxylato Pt(IV) complexes was studied under physiologically relevant conditions...

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Detalles Bibliográficos
Autores principales: Kastner, Alexander, Poetsch, Isabella, Mayr, Josef, Burda, Jaroslav V., Roller, Alexander, Heffeter, Petra, Keppler, Bernhard K., Kowol, Christian R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6766845/
https://www.ncbi.nlm.nih.gov/pubmed/30870571
http://dx.doi.org/10.1002/anie.201900682

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6766845/
https://www.ncbi.nlm.nih.gov/pubmed/30870571
http://dx.doi.org/10.1002/anie.201900682

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