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A Dogma in Doubt: Hydrolysis of Equatorial Ligands of Pt(IV) Complexes under Physiological Conditions
Due to their high kinetic inertness and consequently reduced side reactions with biomolecules, Pt(IV) complexes are considered to define the future of anticancer platinum drugs. The aqueous stability of a series of biscarboxylato Pt(IV) complexes was studied under physiologically relevant conditions...
Autores principales: | Kastner, Alexander, Poetsch, Isabella, Mayr, Josef, Burda, Jaroslav V., Roller, Alexander, Heffeter, Petra, Keppler, Bernhard K., Kowol, Christian R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6766845/ https://www.ncbi.nlm.nih.gov/pubmed/30870571 http://dx.doi.org/10.1002/anie.201900682 |
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