Design, Synthesis, and Activity Evaluation of Novel N-benzyl Deoxynojirimycin Derivatives for Use as α-Glucosidase Inhibitors

To obtain α-glucosidase inhibitors with high activity, 19 NB-DNJDs (N-benzyl-deoxynojirimycin derivatives) were designed and synthesized. The results indicated that the 19 NB-DNJDs displayed different inhibitory activities towards α-glucosidase in vitro. Compound 18a (1-(4-hydroxy-3-methoxybenzyl)-2...

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Detalles Bibliográficos
Autores principales: Zeng, Fanxin, Yin, Zhongping, Chen, Jiguang, Nie, Xuliang, Lin, Ping, Lu, Tao, Wang, Meng, Peng, Dayong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6766931/
https://www.ncbi.nlm.nih.gov/pubmed/31514404
http://dx.doi.org/10.3390/molecules24183309

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6766931/
https://www.ncbi.nlm.nih.gov/pubmed/31514404
http://dx.doi.org/10.3390/molecules24183309

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