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Long‐Read RNA Sequencing Identifies Alternative Splice Variants in Hepatocellular Carcinoma and Tumor‐Specific Isoforms

Alternative splicing (AS) allows generation of cell type–specific mRNA transcripts and contributes to hallmarks of cancer. Genome‐wide analysis for AS in human hepatocellular carcinoma (HCC), however, is limited. We sought to obtain a comprehensive AS landscape in HCC and define tumor‐associated var...

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Detalles Bibliográficos
Autores principales: Chen, Hui, Gao, Feng, He, Mian, Ding, Xiao Fan, Wong, Aikha M., Sze, Siu Ching, Yu, Allen C., Sun, Tingting, Chan, Anthony W‐H., Wang, Xin, Wong, Nathalie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6766942/
https://www.ncbi.nlm.nih.gov/pubmed/30637779
http://dx.doi.org/10.1002/hep.30500