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Flow Cytometry Assessment of CD26(+) Leukemic Stem Cells in Peripheral Blood: A Simple and Rapid New Diagnostic Tool for Chronic Myeloid Leukemia

BACKGROUND: Recent investigations in chronic myeloid leukemia (CML) have focused on the identification and characterization of leukemic stem cells (LSCs). These cells reside within the CD34(+)/CD38(─)/Lin(─) fraction and score positive for CD26 (dipeptidylpeptidase IV) a marker, expressed in both bo...

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Detalles Bibliográficos
Autores principales: Raspadori, Donatella, Pacelli, Paola, Sicuranza, Anna, Abruzzese, Elisabetta, Iurlo, Alessandra, Cattaneo, Daniele, Gozzini, Antonella, Galimberti, Sara, Baratè, Claudia, Pregno, Patrizia, Nicolosi, Maura, Sorà, Federica, Annunziata, Mario, Luciano, Luigiana, Caocci, Giovanni, Moretti, Sabrina, Sgherza, Nicola, Fozza, Claudio, Russo, Sabina, Usala, Emilio, Liberati, Marina A., Ciofini, Sara, Trawinska, Monika M., Gozzetti, Alessandro, Bocchia, Monica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6767040/
https://www.ncbi.nlm.nih.gov/pubmed/30714299
http://dx.doi.org/10.1002/cyto.b.21764