Bone marrow‐derived macrophage contributes to fibrosing steatohepatitis through activating hepatic stellate cells

The role of macrophages in fibrosing steatohepatitis is largely unclear. We characterized the origin and molecular mechanisms of macrophages and its targeted therapy of fibrosing steatohepatitis. Fibrosing steatohepatitis was established in Alms1 mutant (foz/foz) and C57BL/6J wildtype mice fed high‐...

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Detalles Bibliográficos
Autores principales: Han, Juqiang, Zhang, Xiang, Lau, Jennie K‐C, Fu, Kaili, Lau, Harry CH, Xu, Weiqi, Chu, Eagle SH, Lan, Huiyao, Yu, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2019
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6767065/
https://www.ncbi.nlm.nih.gov/pubmed/30945293
http://dx.doi.org/10.1002/path.5275

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6767065/
https://www.ncbi.nlm.nih.gov/pubmed/30945293
http://dx.doi.org/10.1002/path.5275

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