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Complement Activation-Related Pathophysiological Changes in Anesthetized Rats: Activator-Dependent Variations of Symptoms and Mediators of Pseudoallergy

Complement (C) activation can underlie the infusion reactions to liposomes and other nanoparticle-based medicines, a hypersensitivity syndrome that can be partially reproduced in animal models. However, the sensitivities and manifestations substantially differ in different species, and C activation...

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Detalles Bibliográficos
Autores principales: Dézsi, László, Mészáros, Tamás, Őrfi, Erik, Fülöp, Tamás G., Hennies, Mark, Rosivall, László, Hamar, Péter, Szebeni, János, Szénási, Gábor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6767111/
https://www.ncbi.nlm.nih.gov/pubmed/31505853
http://dx.doi.org/10.3390/molecules24183283