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Trilobatin, a Novel SGLT1/2 Inhibitor, Selectively Induces the Proliferation of Human Hepatoblastoma Cells

Studies have indicated that Na(+)-d-glucose co-transporter (SGLT) inhibitors had anti-proliferative activity by attenuating the uptake of glucose in several tumor cell lines. In this study, the molecular docking showed that, trilobatin, one of the dihydrochalcones from leaves of Lithocarpus polystac...

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Detalles Bibliográficos
Autores principales: Wang, Lujing, Liu, Min, Yin, Fei, Wang, Yuanqiang, Li, Xingan, Wu, Yucui, Ye, Cuilian, Liu, Jianhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6767144/
https://www.ncbi.nlm.nih.gov/pubmed/31540429
http://dx.doi.org/10.3390/molecules24183390