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Effects of vatinoxan on cardiorespiratory function and gastrointestinal motility during constant‐rate medetomidine infusion in standing horses

BACKGROUND: Medetomidine suppresses cardiovascular function and reduces gastrointestinal motility in horses mainly through peripheral α(2)‐adrenoceptors. Vatinoxan, a peripheral α(2)‐antagonist, has been shown experimentally to alleviate the adverse effects of some α(2)‐agonists in horses. However,...

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Detalles Bibliográficos
Autores principales: Tapio, H., Raekallio, M. R., Mykkänen, A., Männikkö, S., Scheinin, M., Bennett, R. C., Vainio, O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6767159/
https://www.ncbi.nlm.nih.gov/pubmed/30793362
http://dx.doi.org/10.1111/evj.13085