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IL‐6 counteracts the inhibitory effect of IL‐4 on osteogenic differentiation of human adipose stem cells

Fracture repair is characterized by cytokine production and hypoxia. To better predict cytokine modulation of mesenchymal stem cell (MSC)‐aided bone healing, we investigated whether interleukin 4 (IL‐4), IL‐6, and their combination, affect osteogenic differentiation, vascular endothelial growth fact...

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Detalles Bibliográficos
Autores principales: Bastidas‐Coral, Angela P., Hogervorst, Jolanda M. A., Forouzanfar, Tymour, Kleverlaan, Cornelis J., Koolwijk, Pieter, Klein‐Nulend, Jenneke, Bakker, Astrid D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6767193/
https://www.ncbi.nlm.nih.gov/pubmed/31016754
http://dx.doi.org/10.1002/jcp.28652