Ionic Liquids Enhanced Alkynyl Schiff Bases Derivatives of Fipronil Synthesis and Their Cytotoxicity Studies

To obtain highly selective toxic derivatives of fipronil, a series of Schiff bases with an alkynyl group (3a–3k) were designed and synthesized from 4-ethynylbenzaldehyde (2) and 4-substituted 5-amino-N-arylpyrazole (1a–1k) via a nucleophilic addition elimination reaction in ionic liquids. Utilizatio...

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Detalles Bibliográficos
Autores principales: Liu, Xiu, Huang, Linya, Chen, Hongjun, Li, Na, Yan, Chao, Jin, Chenzhong, Xu, Hanhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6767227/
https://www.ncbi.nlm.nih.gov/pubmed/31487951
http://dx.doi.org/10.3390/molecules24183223

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6767227/
https://www.ncbi.nlm.nih.gov/pubmed/31487951
http://dx.doi.org/10.3390/molecules24183223

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