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Ionic Liquids Enhanced Alkynyl Schiff Bases Derivatives of Fipronil Synthesis and Their Cytotoxicity Studies
To obtain highly selective toxic derivatives of fipronil, a series of Schiff bases with an alkynyl group (3a–3k) were designed and synthesized from 4-ethynylbenzaldehyde (2) and 4-substituted 5-amino-N-arylpyrazole (1a–1k) via a nucleophilic addition elimination reaction in ionic liquids. Utilizatio...
Autores principales: | Liu, Xiu, Huang, Linya, Chen, Hongjun, Li, Na, Yan, Chao, Jin, Chenzhong, Xu, Hanhong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6767227/ https://www.ncbi.nlm.nih.gov/pubmed/31487951 http://dx.doi.org/10.3390/molecules24183223 |
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