Structural Insights into the Regulation Mechanism of Small GTPases by GEFs

Small GTPases are key regulators of cellular events, and their dysfunction causes many types of cancer. They serve as molecular switches by cycling between inactive guanosine diphosphate (GDP)-bound and active guanosine triphosphate (GTP)-bound states. GTPases are deactivated by GTPase-activating pr...

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Detalles Bibliográficos
Autores principales: Toma-Fukai, Sachiko, Shimizu, Toshiyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6767298/
https://www.ncbi.nlm.nih.gov/pubmed/31514408
http://dx.doi.org/10.3390/molecules24183308

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6767298/
https://www.ncbi.nlm.nih.gov/pubmed/31514408
http://dx.doi.org/10.3390/molecules24183308

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